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Cyanidin-3-glucoside

Moderate

Mechanism of Action

Inhibits COX-1 and COX-2 enzyme activity, suppresses NF-κB nuclear translocation, scavenges reactive oxygen species via electron donation from the flavylium ring system, and upregulates Nrf2/HO-1 antioxidant pathway. Enhances rhodopsin regeneration in retinal rod photoreceptors and improves retinal microcirculation.
Neuraminidase inhibition prevents viral attachment and entry; immunomodulation via cytokine production (IL-6, IL-8, TNF-alpha)

Research Notes

Randomized controlled trials have demonstrated significant improvements in dark adaptation and visual acuity under low-light conditions with blackcurrant anthocyanin supplementation. A 2020 crossover RCT (n=34) showed reduced exercise-induced oxidative stress markers and maintained muscle function compared to placebo. In vitro and rodent studies consistently demonstrate COX inhibition and NF-κB suppression at physiologically relevant concentrations.

ElderberryWestern

A systematic review of RCTs shows elderberry supplementation significantly reduces duration and severity of upper respiratory infections. In vitro studies confirm direct antiviral activity against influenza A and B strains.

Found In 2 Herbs

3D Molecular Structure

Anthocyanin (flavonoid glycoside)
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Cyanidin-3-glucoside

Anthocyanin (flavonoid glycoside)Polyphenolic antioxidants protecting cells from oxidative damage

Representative pattern: C₁₅H₁₀O₃

Atoms
Carbon
Oxygen

Live Research

Open on PubMed

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