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Crofelemer (SP-303)

Clinical trial

Mechanism of Action

Inhibits CFTR and CaCC chloride channels in intestinal epithelium, reducing chloride and water secretion into the gut lumen

Research Notes

Dragon's BloodSouth American

Crofelemer was developed from dragon's blood and approved by the FDA as Mytesi for HIV-associated non-infectious diarrhoea. It acts locally in the gut without systemic absorption.

Found In 1 Herb

3D Molecular Structure

Oligomeric proanthocyanidin
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Crofelemer (SP-303)

Oligomeric proanthocyanidinBioactive phytochemical with therapeutic properties

Representative pattern: C₄H₂NO

Atoms
Carbon
Oxygen
Nitrogen
Hydrogen

Live Research

Open on PubMed

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