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Crocin

In vitro / Animal

Mechanism of Action

Antioxidant, neuroprotective, antidepressant via serotonin/dopamine modulation, anti-inflammatory
Antidepressant via serotonin reuptake inhibition, neuroprotective via antioxidant, anti-inflammatory, cardioprotective, anti-Alzheimer\'s

Research Notes

Antidepressant effects comparable to fluoxetine in animal models. Neuroprotective against Aβ toxicity. Same compound as in Crocus sativus (saffron) — responsible for yellow color.

SaffronAyurvedic

Antidepressant effect comparable to fluoxetine and imipramine in RCTs (30mg/day). Improved memory in Alzheimer\'s patients (pilot RCT). Neuroprotective in multiple neurodegeneration models.

Found In 2 Herbs

3D Molecular Structure

Carotenoid glycoside
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Crocin

Carotenoid glycosideSugar-bound molecules that control drug release in the body

Representative pattern: C₁₁H₁₄O₆

Atoms
Carbon
Oxygen

Live Research

Open on PubMed

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