Cordycepic acid (D-mannitol)

Traditional use

Mechanism of Action

Acts as an osmolyte in renal tubular cells, supporting kidney function and diuresis. Demonstrates antioxidant properties by scavenging hydroxyl radicals. May improve cerebral and peripheral blood flow through reduction of blood viscosity. Also acts as a cough suppressant through mechanisms related to bronchial mucosa hydration.

Research Notes

Cordyceps sinensis (Wild Caterpillar Fungus)Mushroom

D-mannitol is not unique to Cordyceps but is present in unusually high concentrations (7–12% of dry weight in wild specimens). Chinese pharmacopoeia requires ≥7% mannitol as a quality standard for O. sinensis. While D-mannitol itself is well-characterized pharmacologically (used clinically as an osmotic diuretic), its specific contribution to O. sinensis's traditional effects is difficult to isolate from other bioactives. Cordycepic acid content is used as a primary authentication marker for genuine O. sinensis.

Found In 1 Herb

Cordyceps sinensis (Wild Caterpillar Fungus)

Mushroom

3D Molecular Structure

Sugar alcohol (polyol)

Drag to rotate · Click atoms to explore

Cordycepic acid (D-mannitol)

Sugar alcohol (polyol)Bioactive phytochemical with therapeutic properties

Representative pattern: C₄H₂NO

Atoms

Carbon

Oxygen

Nitrogen

Hydrogen

Live Research

Open on PubMed

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