Cinnamaldehyde

Clinical trial

Mechanism of Action

Primary bioactive volatile compound; provides antimicrobial, anti-inflammatory, and insulin-sensitizing activity through TRPA1 receptor activation and inhibition of NF-κB inflammatory pathways

Insulin sensitization via GLUT4 translocation, anti-inflammatory via NF-kB, antimicrobial, thermogenic via TRPA1, vasodilatory

Warming via TRPA1 channel activation; diaphoretic; anti-inflammatory; vasodilatory

Research Notes

CinnamonAyurvedic

Well-characterized primary bioactive in cinnamon with strong evidence for antimicrobial, anti-inflammatory, and insulin-sensitizing activity through multiple mechanisms.

Cinnamon Bark (Rou Gui)TCM

Improved insulin sensitivity and fasting glucose in type 2 diabetes RCTs. Antimicrobial against C. albicans and H. pylori. Thermogenic effect via TRPA1 receptor — pharmacological basis for TCM 'hot' nature.

Cinnamon Twig (Gui Zhi)TCM

Cinnamaldehyde is the primary aromatic compound in cinnamon twig. Clinical evidence supports warming, diaphoretic, and anti-inflammatory effects.

Found In 3 Herbs

3D Molecular Structure

Phenylpropanoid aldehyde

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Cinnamaldehyde

Phenylpropanoid aldehydeBioactive phytochemical with therapeutic properties

Representative pattern: C₇H₆O₃

Atoms

Carbon

Oxygen

Hydrogen

Live Research

Open on PubMed

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