Cayaponoside

In vitro

Mechanism of Action

A glycosylated cucurbitacin with improved water solubility and reduced direct cytotoxicity compared to aglycone forms. Contributes to anti-inflammatory activity through NF-kB and MAPK pathway modulation. May serve as a prodrug, with the sugar moiety cleaved by intestinal glucosidases to release active cucurbitacin.

Research Notes

TayuyaSouth American

Identified and characterized from C. tayuya root by Brazilian researchers. In vitro anti-inflammatory assays showed inhibition of NO production in LPS-stimulated macrophages at concentrations less cytotoxic than cucurbitacin B, suggesting a potentially wider therapeutic window. The glycoside form showed better oral bioavailability in preliminary animal pharmacokinetic studies.

Found In 1 Herb

Tayuya

South American

3D Molecular Structure

Cucurbitane glycoside

Drag to rotate · Click atoms to explore

Cayaponoside

Cucurbitane glycosideSugar-bound molecules that control drug release in the body

Representative pattern: C₁₁H₁₄O₆

Atoms

Carbon

Oxygen

Live Research

Open on PubMed

This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare practitioner before using any herbal product.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This content is for educational purposes only and is not a substitute for professional medical advice.