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Casticin
In vitro / AnimalMechanism of Action
COX-2 inhibition; anti-inflammatory via PGE2 suppression; analgesic; anti-allergic (mast cell stabilisation)
Progesterone receptor modulation; anti-inflammatory signaling
Research Notes
NirgundiAyurvedic
Selective COX-2 inhibition documented in vitro. Analgesic effects comparable to aspirin in tail-flick test. Anti-allergic via mast cell membrane stabilisation.
Vitex (Chaste Tree)Western
Casticin exhibits estrogenic and progestagenic activity in receptor binding assays. Contributes to anti-inflammatory effects observed in menstrual disorder studies.
Found In 2 Herbs
3D Molecular Structure
Polymethoxyflavone
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Casticin
PolymethoxyflavoneBioactive phytochemical with therapeutic properties
Representative pattern: C₁₅H₁₀O₃
Atoms
Carbon
Oxygen
Related Compounds (Polymethoxyflavone)
Live Research
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