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Casticin

In vitro / Animal

Mechanism of Action

COX-2 inhibition; anti-inflammatory via PGE2 suppression; analgesic; anti-allergic (mast cell stabilisation)
Progesterone receptor modulation; anti-inflammatory signaling

Research Notes

NirgundiAyurvedic

Selective COX-2 inhibition documented in vitro. Analgesic effects comparable to aspirin in tail-flick test. Anti-allergic via mast cell membrane stabilisation.

Casticin exhibits estrogenic and progestagenic activity in receptor binding assays. Contributes to anti-inflammatory effects observed in menstrual disorder studies.

Found In 2 Herbs

3D Molecular Structure

Polymethoxyflavone
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Casticin

PolymethoxyflavoneBioactive phytochemical with therapeutic properties

Representative pattern: C₁₅H₁₀O₃

Atoms
Carbon
Oxygen

Related Compounds (Polymethoxyflavone)

Live Research

Open on PubMed

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