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Carnosic acid

Animal

Mechanism of Action

Potent antioxidant; inhibits lipid peroxidation; neuroprotective via free radical scavenging
Activates Nrf2 antioxidant pathway; neuroprotective through BDNF upregulation

Research Notes

RosemaryWestern

Carnosic acid demonstrates superior antioxidant capacity protecting vascular lipids from oxidation. Inhibits neuroinflammation relevant to cardiovascular disease. Primary diterpenoid in Rosemary extracts.

SageWestern

Carnosic acid activates the Nrf2 cellular defence pathway. Animal studies show it crosses the blood-brain barrier and upregulates brain-derived neurotrophic factor (BDNF).

Found In 2 Herbs

3D Molecular Structure

Abietane diterpene
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Carnosic acid

Abietane diterpeneAromatic plant metabolites with anti-inflammatory properties

Representative pattern: C₁₀H₁₆O

Atoms
Carbon
Oxygen
Hydrogen

Live Research

Open on PubMed

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