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Capsaicin
Clinical trialMechanism of Action
TRPV1 (vanilloid receptor 1) agonist; initial activation followed by desensitization; depletes substance P in sensory neurons for analgesic effect
Research Notes
Cayenne (Capsicum)Western
Capsaicin is the pungent alkaloid in hot peppers with extensive clinical evidence for topical analgesia in arthritis and musculoskeletal pain. Topical application desensitizes pain nerve endings; effects develop over days to weeks and provide sustained relief.
Found In 1 Herb
3D Molecular Structure
Vanilloid alkaloid (N-vanillyl-6-methylhept-5-enamide)
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Capsaicin
Vanilloid alkaloid (N-vanillyl-6-methylhept-5-enamide)Nitrogen-containing compounds with potent pharmacological effects
Representative pattern: C₉H₇N₂O
Atoms
Nitrogen
Carbon
Hydrogen
Oxygen
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