Betaine

Moderate

Trimethylglycine (quaternary ammonium compound)

Mechanism of Action

Betaine acts as a methyl donor in the liver, converting homocysteine to methionine via betaine-homocysteine methyltransferase (BHMT), thereby reducing homocysteine levels and supporting hepatic methylation capacity. It also functions as an osmolyte, protecting cells against osmotic stress by stabilizing protein structures and maintaining cell volume.

Research Notes

Cotton Root BarkWestern

Betaine is FDA-approved (Cystadane) for the treatment of homocystinuria. Clinical trials demonstrate significant homocysteine reduction in patients with elevated levels. In the context of cotton root bark, betaine contributes to hepatoprotective effects that may partially offset gossypol's hepatotoxic potential. Betaine content in cotton root bark is relatively modest compared to dedicated betaine supplements.

Found In 1 Herb

Cotton Root Bark

Western

3D Molecular Structure

Trimethylglycine (quaternary ammonium compound)

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Betaine

Trimethylglycine (quaternary ammonium compound)Bioactive phytochemical with therapeutic properties

Representative pattern: C₄H₂NO

Atoms

Carbon

Oxygen

Nitrogen

Hydrogen

Live Research

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