Baccharin

Animal

Mechanism of Action

Provides gastroprotective activity through stimulation of gastric mucus secretion, enhancement of mucosal prostaglandin E2 production, and inhibition of H+/K+-ATPase (proton pump). Also exhibits anti-inflammatory activity through NF-kB pathway suppression in gastric epithelial cells.

Research Notes

CarquejaSouth American

Animal studies using ethanol- and indomethacin-induced gastric ulcer models demonstrated that baccharin reduced ulcer index by 60–80% compared to controls, comparable to omeprazole at the tested doses. A 2009 study in Chemico-Biological Interactions showed baccharin's antitumor activity against Ehrlich tumor cells in mice, with mechanism involving increased apoptosis markers.

Found In 1 Herb

Carqueja

South American

3D Molecular Structure

Clerodane diterpene

Drag to rotate · Click atoms to explore

Baccharin

Clerodane diterpeneAromatic plant metabolites with anti-inflammatory properties

Representative pattern: C₁₀H₁₆O

Atoms

Carbon

Oxygen

Hydrogen

Live Research

Open on PubMed

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