Astragalus Polysaccharides (APS)

Strong

Heteropolysaccharide complex (predominantly glucans and galacturonans)

Mechanism of Action

Immunostimulatory via multiple TLR activation (TLR-4, TLR-2), complement receptor stimulation, and macrophage/dendritic cell maturation; enhances NK cell cytotoxicity and CTL activity; anti-fatigue via muscle glycogen preservation; antidiabetic via AMPK activation and pancreatic β-cell protection; hematopoietic support via G-CSF and GM-CSF upregulation

Research Notes

Astragalus (Huang Qi)TCM

Systematic reviews of RCTs demonstrate APS reduces chemotherapy-induced myelosuppression in cancer patients receiving platinum-based regimens. Antidiabetic effects (HbA1c and fasting glucose reduction) confirmed in a small RCT. Hepatoprotective effects in hepatitis B patients in Chinese clinical settings.

Found In 1 Herb

Astragalus (Huang Qi)

TCM

3D Molecular Structure

Heteropolysaccharide complex (predominantly glucans and galacturonans)

Drag to rotate · Click atoms to explore

Astragalus Polysaccharides (APS)

Heteropolysaccharide complex (predominantly glucans and galacturonans)Complex carbohydrate polymers that modulate immune response

Representative pattern: (C₆H₁₀O₅)ₙ

Atoms

Carbon

Oxygen

Live Research

Open on PubMed

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