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Aristolochic acid I
Clinical trialMechanism of Action
IARC Group 1 carcinogen; covalently binds to DNA forming aristolactam-DNA adducts; causes progressive tubulo-interstitial nephropathy
Research Notes
AsarabaccaWestern
Definitive human carcinogen with well-established mechanism of DNA adduct formation and nephrotoxicity.
Found In 1 Herb
3D Molecular Structure
Nitrophenanthrene carboxylic acid
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Aristolochic acid I
Nitrophenanthrene carboxylic acidBioactive phytochemical with therapeutic properties
Representative pattern: C₄H₂NO
Atoms
Carbon
Oxygen
Nitrogen
Hydrogen
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