Anandamide

In vitro

Mechanism of Action

Binds CB1 and CB2 cannabinoid receptors; modulates mood, pain perception, and appetite; effects are prolonged by N-acylethanolamine inhibitors also present in cacao

Research Notes

CacaoSouth American

Cacao contains anandamide and two structural analogs (N-oleoylethanolamine and N-linoleoylethanolamine) that inhibit anandamide breakdown, potentially prolonging its endocannabinoid effects. Concentrations in cacao are very low, and the clinical significance of dietary anandamide intake remains debated. In vitro evidence supports the mechanism.

Found In 1 Herb

Cacao

South American

3D Molecular Structure

Endocannabinoid (N-acylethanolamine)

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Anandamide

Endocannabinoid (N-acylethanolamine)Bioactive phytochemical with therapeutic properties

Representative pattern: C₄H₂NO

Atoms

Carbon

Oxygen

Nitrogen

Hydrogen

Live Research

Open on PubMed

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