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Anandamide
In vitroMechanism of Action
Binds CB1 and CB2 cannabinoid receptors; modulates mood, pain perception, and appetite; effects are prolonged by N-acylethanolamine inhibitors also present in cacao
Research Notes
CacaoSouth American
Cacao contains anandamide and two structural analogs (N-oleoylethanolamine and N-linoleoylethanolamine) that inhibit anandamide breakdown, potentially prolonging its endocannabinoid effects. Concentrations in cacao are very low, and the clinical significance of dietary anandamide intake remains debated. In vitro evidence supports the mechanism.
Found In 1 Herb
3D Molecular Structure
Endocannabinoid (N-acylethanolamine)
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Anandamide
Endocannabinoid (N-acylethanolamine)Bioactive phytochemical with therapeutic properties
Representative pattern: C₄H₂NO
Atoms
Carbon
Oxygen
Nitrogen
Hydrogen
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