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Aloin
Clinical trialMechanism of Action
Stimulates colonic peristalsis by inhibiting water and electrolyte absorption in the colon; increases mucosal secretion via prostaglandin-mediated mechanism; irritant laxative effect through direct action on enteric neurons
Research Notes
Aloe VeraWestern
Aloin is a potent stimulant laxative with well-established pharmacology. The FDA reclassified aloe latex laxatives as Category III (insufficient data for GRAS status) in 2002. Chronic use is associated with melanosis coli and electrolyte disturbance. Animal studies have raised concerns about carcinogenicity of whole-leaf extracts containing aloin.
Found In 1 Herb
3D Molecular Structure
Anthraquinone glycoside (barbaloin)
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Aloin
Anthraquinone glycoside (barbaloin)Sugar-bound molecules that control drug release in the body
Representative pattern: C₁₁H₁₄O₆
Atoms
Carbon
Oxygen
Live Research
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