Aloin

Clinical trial

Mechanism of Action

Stimulates colonic peristalsis by inhibiting water and electrolyte absorption in the colon; increases mucosal secretion via prostaglandin-mediated mechanism; irritant laxative effect through direct action on enteric neurons

Research Notes

Aloe VeraWestern

Aloin is a potent stimulant laxative with well-established pharmacology. The FDA reclassified aloe latex laxatives as Category III (insufficient data for GRAS status) in 2002. Chronic use is associated with melanosis coli and electrolyte disturbance. Animal studies have raised concerns about carcinogenicity of whole-leaf extracts containing aloin.

Found In 1 Herb

Aloe Vera

Western

3D Molecular Structure

Anthraquinone glycoside (barbaloin)

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Aloin

Anthraquinone glycoside (barbaloin)Sugar-bound molecules that control drug release in the body

Representative pattern: C₁₁H₁₄O₆

Atoms

Carbon

Oxygen

Live Research

Open on PubMed

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