Aloe-emodin

In vitro

Mechanism of Action

Induces apoptosis in cancer cell lines via mitochondrial pathway and caspase activation; exhibits cathartic activity similar to other anthraquinones; anti-inflammatory through NF-kB inhibition

Research Notes

Aloe VeraWestern

Aloe-emodin has shown selective cytotoxicity against several human cancer cell lines including liver, lung, and leukemia cells in vitro. However, it also demonstrates genotoxic potential in bacterial mutagenicity assays. Clinical relevance for anticancer applications remains unestablished, and safety concerns limit internal use of concentrated preparations.

Found In 1 Herb

Aloe Vera

Western

3D Molecular Structure

Anthraquinone (hydroxyanthraquinone)

Drag to rotate · Click atoms to explore

Aloe-emodin

Anthraquinone (hydroxyanthraquinone)Bioactive phytochemical with therapeutic properties

Representative pattern: C₄H₂NO

Atoms

Carbon

Oxygen

Nitrogen

Hydrogen

Live Research

Open on PubMed

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