Agaric Acid (Agaricin)

Preliminary

Mechanism of Action

Agaric acid exerts parasympatholytic (anticholinergic-like) and anhidrotic (sweat-reducing) effects, explaining its historical use for night sweats in tuberculosis patients. It stimulates macrophage activation and promotes production of pro-inflammatory cytokines TNF-α and IL-6, supporting innate immune defense against intracellular pathogens. Anti-inflammatory properties occur through modulation of arachidonic acid metabolism, providing analgesic effects complementary to its antimicrobial actions.

Research Notes

AgarikonMushroom

Historical pharmacological studies confirmed anhidrotic and parasympatholytic activity, consistent with traditional indications for night sweats. Modern in vitro studies demonstrated macrophage cytokine production enhancement. Anti-inflammatory activity confirmed in multiple assay systems. Agaric acid has been used historically in European pharmaceutical preparations but has not been subject to modern randomized clinical trials.

Found In 1 Herb

Agarikon

Mushroom

3D Molecular Structure

Fatty acid derivative

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Agaric Acid (Agaricin)

Fatty acid derivativeBioactive phytochemical with therapeutic properties

Representative pattern: C₄H₂NO

Atoms

Carbon

Oxygen

Nitrogen

Hydrogen

Live Research

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